David Walk, MD


Academic Title

Associate Professor

Clinical Title

University of Minnesota Physician


Medical School
Brown University
Providence, Rhode Island

New York University
University of Chicago

Resident Physician in ALS
University of Chicago

Clinical Neurophysiology
Michael Reese Hospital
Chicago, Illinois

Contact Info


Office Phone Number

Office Fax Number

Administrative Contact
Sean McFaggen

Office Address
Department of Neurology
University of Minnesota
420 Delaware St. SE
Minneapolis, MN 55455

Mailing Address
Department of Neurology
University of Minnesota
MMC 295, 420 Delaware St. SE
Minneapolis, MN 55455

More Information

Bio Statement

Dr. David Walk is a neurologist at the University of Minnesota Medical Center Fairview with a subspecialty interest in neuromuscular diseases. Dr. Walk currently directs the University of Minnesota's multidisciplinary ALS and Charcot-Marie-Tooth clinics. Named a "top doctor" by Minneapolis St. Paul Magazine, he believes that the management of neuromuscular disorders requires a team dedicated to providing comprehensive care.

Dr. Walk has been an Associate Professor of Neurology at the University of Minnesota Medical School since 2005 and a staff neurologist at the University of Minnesota Medical Center, Fairview since 1999; he is also the Medical Director of the electromyography laboratory.

Research Interests

Dr. Walk's research interests include ALS and other motor neuron disorders, Charcot-Marie-Tooth disease, and quantitative sensory testing in patients with neuropathic pain.

Research Projects

Dr. Walk's ongoing research projects are focused on ALS as well as sensory evaluation in neuropathy and neuropathic pain. He was the Principal Investigator of a study entitled “Quantitative Sensory Testing in Pathologic Pain States” sponsored by the Minnesota Medical Foundation and the local Principal Investigator of a study sponsored by the University of Minnesota Clinical and Translational Science Institute involving chemotherapy-induced peripheral neuropathy. Ongoing research projects in the neuromuscular section include a longitudinal study of imaging biomarkers in ALS, a prospective evaluation of quantitative sensory testing in pathologic pain, and the assessment of A-delta and C-fiber small nerve function in established chemotherapy-associated neuropathy.

Selected Peer-Reviewed Publications

Walk D, Zaretskaya M, Parry GJ. Symptom duration and clinical features in painful sensory neuropathy with and without nerve conduction abnormalities. J Neurol Sci 2003;214:3-6.

Mulrooney DA, Davies SM, Walk D, Charnas LR. Chronic Immune Mediated Axonal Polyneuropathy following Bone Marrow Transplant for Juvenile Onset Alpha-Mannosidosis. Bone Marrow Transplant 2003;9:953-5.

Walk D, Li LY, Parry GJ, Day JW. Rapid Resolution of Quadriplegic CIDP by Combined Plasmapheresis and IVIg. Neurology 2004;62:155-6.

Wendelschafer-Crabb G, Kennedy WR, Walk D. Morphological Features of Nerves in Skin Biopsies. J Neurol Sci 242 (2006), 15-21.

Walk D, Wendelschafer-Crabb G, Davey C, Kennedy WR. Concordance between epidermal nerve fiber density and sensory examination in patients with symptoms of idiopathic small fiber neuropathy. J Neurol Sci. 2007;255:23-26.

Schwarzenberg SJ, Thomas W, Olsen TW, Grover T, Walk D, Milla C, Moran A. Microvascular complications in cystic fibrosis-related diabetes. Diabetes Care 2007;30:1056-61.

Segal B, Carpenter A, Walk D. Involvement of nervous system pathways in primary Sjogren's syndrome. Rheum Dis Clin North Am. 2008;34:885-906.

Walk D. Skin biopsy in the evaluation of neuropathic pain. Curr Pain Headache Rep 2009; 13:191-196.

Backonja M, Walk D, Edwards RE, Moeller-Bertram T, Sehgal N, Wasan A, Irving G, Argoff C, Wallace M. Quantitative sensory testing (QST) in measurement of neuropathic pain phenomena and other sensory abnormalities. Clin J Pain 2009;25:625-631.

Walk D, Sehgal N, Moeller-Bertram T, Edwards RE, Wasan A, Wallace M, Irving G, Argoff C, Backonja M-M. Quantitative sensory testing and mapping: a review of non-automated quantitative methods for examination of the patient with neuropathic pain. Clin J Pain 2009;25:632-640.

Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group. Modern-day clinical course of type 1 diabetes mellitus after 30 years' duration: the diabetes control and complications trial/epidemiology of diabetes interventions and complications and Pittsburgh epidemiology of diabetes complications experience (1983-2005). Arch Intern Med. 2009;169:1307-1316.

Kennedy WR, Vanhove GF, Lu SP, Tobias J, Bley KR, Walk D, Wendelschafer-Crabb G, Simone DA, Selim MM. A Randomized, Controlled, Open-Label Study of the Long-Term Effects of NGX-4010, a High-Concentration Capsaicin Patch, on Epidermal Nerve Fiber Density and Sensory Function in Healthy Volunteers. J Pain 2010;11:579-587.

Selim MM, Wendelschafer-Crabb G, Redmon JB, Khoruts A, Hodges JS, Koch K, Walk D, Kennedy WR. Gastric mucosal nerve density: a biomarker for diabetic autonomic neuropathy? Neurology 2010;75:973-981.

Walk D, Backonja M-M. Painful Neuropathies. In Bonica's Management of Pain. 4th ed. Philadelphia: Wolters Kluwer Health/Lippincott, Williams and Wilkins c2010.

Backonja MM, Walk D. QST in peripheral nerve injury pain disorders. Pain 2012; 153:736-737.

Walk D, Backonja M. HIV neuropathy continues to pose a challenge. Pain Med 2013; 14:957-958.