Ongoing Clinical Trials

Clinical trials are controlled research studies conducted to investigate alternative treatments for patients with medical, surgical, neurological or psychiatric disorders. Physicians in the Department of Neurology participate in a number of clinical trials related to specific neurological disorders.

ALS

1. Genomic Translation for ALS Care; NCT: NCT02795897.

2. A Phase 2 Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of NP001 in Subjects with Amyotrophic Lateral Sclerosis (ALS) and Evidence of Elevated Systemic Inflammations; NCT: NCT02794857.

Ataxia

Clinical Research Consortium for Spinocerebellar Ataxias (CRC-SCA) to Study Natural History and Genetic Modifiers in Spinocerebellar Ataxia; NCT: NCT01060371.

CIDP

Intravenous Immunoglobulin (IVIg) Treatment-Related Fluctuations in Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) Patients Using Daily Grip Strength Measurements (GRIPPER); NCT: NCT02414490.

CMT

1. A Natural History Study of CMT1B, CMT2A, CMT4A and CMT4C; NCT: NCT01193075.

2. Genetics of CMT — Modifiers of CMT1A, New Causes of CMT; NCT: NCT01060371.

Idiopathic Neuropathy

Clinical Research Consortium for Spinocerebellar Ataxias (CRC-SCA) to Study Natural History and Genetic Modifiers in Spinocerebellar Ataxia; NCT: NCT01060371.

Multiple Sclerosis

Treatment of progressive forms of Multiple Sclerosis with pulsed ACTH (Acthar Gel); NCT: NCT01950234.

Diabetic Peripheral Neuropathy

A Phase III, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to Assess the Safety and Efficacy of VM202 in Subjects with Painful Diabetic Peripheral Neuropathy; NCT: NCT02427464.

Parkinson's Disease

Neurophysiological Mechanisms Underlying Parkinsonian Motor Signs.